That scientist was harald zur hausen, md, professor emeritus currently working at the german cancer research center, in heidelberg, and. Longterm followup of human papillomavirus vaccine efficacy. The city also contained a womens subcamp of the buchenwald concentration camp. Zur hausen and his research team extracted hpv dna from the tumor samples, and copied and amplified the hpv dna in order to identify the strains. Harald zur hausen, a genman noble prizewinner of physiologymedicine in 2008 discovered that the high risk type hpv hrhpvinduced cervical cancer. If hsv2 was already in the samples, the single strand would bind to its complementary half in the samples.
Harald zur hausen delivered his nobel lecture on 7 december 2008 at. Vogt pdf the role of viruses in human leukemia a summary. Nobel prize for medicine awarded to harald zur hausen. Han ar ocksa kand som mangarig huvudredaktor for tidskriften international journal of cancer.
Initially, zur hausen, working in the university of pennsylvania. Media in category harald zur hausen the following 24 files are in this category, out of 24 total. Jun 19, 2015 harald zur hausen was a child in germany during the second world war, growing up in gelsenkirchenbuer, which was then a center for german coal production and oil refining and, consequently, a major target for allied bombing. Studying in germany a good choice for your child 15 questions and answers. Professor patrick arbuthnot, dr geoff candy, professors julian oettle, franco guidozzi, and david lewis at the panel discussion. Millions have been driven from their homes, families have been divided, and entire communities torn apart.
Harald zur hausen awarded nobel prize for medicine. Harald zur hausen 1936 harald zur hausen studied viruses and. Harald zur hausen, longtime chairman of the board of the german cancer research centre dkfz and honorary professor of the university of heidelberg, has been awarded the nobel prize for medicine. An estimated 100 000 people have been killed, most of them civilians, and many more have been wounded, tortured, or abused. Harald zur hausen and colleagues found hpv 16 and 18 in 70% of specimens of cervical cancer iarc follows up 1984. Harald zur hausen press conference dec 06th, 20084. Studying in germany a good choice for your child 15. Scientometric portrait of nobel laureate harald zur. View enhanced pdf access article on wiley online library html view download pdf for offline viewing. Harald zur hausen by using hausens research, a vaccine was eventually developed a vaccine. Harald zur hausen, german virologist who was a corecipient, with fran. Harald zur hausen delivered his nobel lecture on 7 december 2008 at karolinska institutet in stockholm. Vaccine request denied 1990 aids conference virus like particlesvlps. A new type of papillomavirus dna, its presence in genital cancer biopsies and in cell lines derived from cervical cancer pdf.
Harald zur hausen, medicine 2008 peter higgs, physics 20 jules a. Nobelwinning discovery of hpvcervical cancer link already. Nubia munoz and her colleagues, research over the past decades has shown infection with certain cancercausing types of human papillomavirus hpv to be. Soon fasttesting hpv methods and vaccines were developed to prevent cervical cancer effectively.
Booklet harald zur hausen nobel prize in medicine 2008. Harald zur hausens experiments on human papillomavirus. Methodenforschung zur fruherkennung des krebses special research program of the german science foundation dfg, university of erlangennurnberg, germany 1979 1983 sprecher chairman of the sonderforschungsbereich 118 medizinische virologie. Viruses in human tumors haematology and blood transfusion vol. Publications according to topics pdf 5 most important publications pdf publications at science connections. Harald zur hausen date of birth march 11, 1936 place of birth gelsenkirchen, germany marital state married with dr. Thirty years later we stand on the threshold of a vaccine to prevent this major killer of women. Department of applied tumor virology harald zur hausen 20012004 ph. Harald zur hausen by using hausen s research, a vaccine was eventually developed a vaccine. Advantages of hpv screening hpv testing is more sensitive than cytology hpv testing has a high negative predictive value hpv testing is automatable and reproducible. Zur hausen and his research team studied hpvcaused genital wart samples and compared the dna in the wart samples to the dna in the cervical cancer tumors. Fabien calvo, maria da graca carvalho, alexander eggermont, ingemar ernberg, jesper fisker, harald zur hausen, bengt jonsson, pernilla lagergren, francesco.
The german academic exchange service daad is a joint organisation of german institutions of higher education and student. Asco s targeted agent and profiling utilization registry tapur study is a nonrandomized clinical trial aiming to describe the performance of commercially available, targeted anticancer drugs prescribed for treatment of patients with advanced cancer with a potentially actionable genomic variant. Hoffmann, physiology or medicine 2011 robert huber, chemistry 1988 tim hunt, physiology or medicine 2001 eric kandel, physiology or medicine 2000 wolfgang ketterle, physics 2001 bernhard lown, peace 1985 luc montagnier, medicine 2008 erwin neher, physics 1991. Harald zur hausen first suggested the concept of oncogenic highrisk hpv in 1975, before confirming hpvs link to cervi cal cancer in 1983. Zur hausen introduced a single strand of hsv2 dna, composed of nucleic acids, the building blocks of dna and rna, into cervical tumor samples. Harald zur hausen press conference dec 06th, 20086. Then, between 1996 and 2001 hpv were proven to cause.
Harald zur hausen was born on march 11, 1936 in gelsenkirchenbuer, germany. Zur hausen was given half the award in recognition of his discovery of the human papilloma virus hpv and its link to cervical cancer. His research made it possible to develop a vaccine against one of the most frequent cancer in women. Professor harald zur hausen, nobel laureate for 2008 in medicine or physiology for his work on human papillomavirus and carcinoma of the cervix, visited wits from 16 to 18 march 2011. More than 70 years later, harald zur hausen demonstrated that human papillomavirus hpv can cause cervical cancer, for which he garnered. Harald zur hausen probable highrisk hpv 16, 18, 45, 31, 33, 52, 58 and 35 8 most common genotypes are responsible fot 90% of all cervical cancers cervical adenocarcinoma. He was introduced by professor bjorn vennstrom, member of the nobel committee for physiology or medicine.
Permission is granted to copy, distribute andor modify this document under the terms of the gnu free documentation license, version 1. A good choice for your child 15 questions and answers for parents 2nd edition. Pdf highlights quantitatively the publication productivity of harald zur hausen a renowned scientist and nobel laureate in physiology who was honoured. With the majority of hpv cases being found in poorer, less developed countries, hausen was appaled. Harald zur hausen, nobel prize laureate for physiology or medicine 2008, at a press. Humana cancersjukdomar som har samband med infektioner. Papillomaviruses in the causation of human cancers a brief. Harald zur hausen and his group, that human papilloma virus 16 can. The conflict in syria has led to what is arguably one of the worlds worst humanitarian crises since the end of the cold war. Harald zur hausen received the 2008 nobel prize in physiology or medicine for his discovery of the link between human papillomavirus hpv infections and genital cancers, he completed a 40year odyssey to prove that viruses caused human cancer.
Dairy cattle meat and milk factors contributing to the risk of cancers and multiple sclerosis. And in 2009, a german biotechstartupcompany had licensed a trifunctional antibody it developed to treat cancerrelated ascites. Harald zur hausen 1936 was awarded a share of the 2008 nobel prize in physiology or medicine for discovering that papillomaviruses cause cervical cancer. Humana cancersjukdomar som har samband med infektioner harald zur hausen. A global epidemiological analysis of the incidence of colon and breast cancers suggests that consumption of meat and milk products of eurasian dairy cattle contributes to the risk for these malignancies. Zur hausen, former scientific director of the german cancer research center, a member of the helmholtz association, is recognized for finding that cervical cancer is caused by viral infections. Harald zur hausen 1936 the embryo project encyclopedia. Scientometric portrait of nobel laureate harald zur hausen.
In 2008, zur hausen was awarded the nobel prize for medicine for his research. Zur hausens nucleic acid hybridization repeatedly failed to find any hsv2 dna in the samples. Papillomaviruses in the causation of human cancers a. Professor zur hausen har flere band till finland och ar bl. Harald zur hausen is a german virologist and professor emeritus. Harald zur hausen, papillomaviruses, and cervical cancer. By using insitu hybridisations, in 1973 we were able to document the. What links here related changes upload file special pages permanent link page. Highlights quantitatively the publication productivity of harald zur hausen a renowned scientist and nobel laureate in physiology who was honoured with nobel prize for the discovery of human papilloma viruses causing cervical cancer. Book highlights excerpts hpv transmission and natural history a silent epidemic. Student, weill graduate school medical sciences of cornell universitymemorial sloankettering cancer center, ny, ny, immunology program, laboratory of antimicrobial immunity thesis advisor. He had 285 publications during 1964 2009 in four domains. Journal of the national cancer institute, volume 92, issue 9. Harald zur hausen and colleagues found hpv 16 and 18 in 70% of specimens of cervical cancer iarc follows up.
1579 1643 104 55 1653 1042 1363 1643 841 914 115 1487 989 572 513 1366 476 1626 24 415 1347 872 1084 824 1491 1268 933 148 762 1123 30 625 1044